Research Update in
Neuroscience for Neurosurgeons

Lori Setton
Duke University

Reading List

Tissue and Cellular Engineering Approaches to Regeneration and Repair of the Intervertebral Disc

1. *Jean D. Sipe
   Tissue Engineering and Reparative Medicine
   Ann NY Acad Sci 2002 961: 1-9.
   
   
2. Butler, D., S.A. Goldstein & F. Guilak. 2000.
   Functional tissue engineering: the role of biomechanics.
   J. Biomech. Eng. 122: 570-575.
   
   
3. *Langer R, Tirrell DA.
   Designing materials for biology and medicine.
   Nature. 2004 Apr 1;428(6982):487-92.
   
   

Basic Science: Intervertebral Disc and Pathology

1. Oegema TR Jr.
   Biochemistry of the intervertebral disc.
   Clin Sports Med. 1993 Jul;12(3):419-39.
   
   
2. Bogduk N.
   The lumbar disc and low back pain.
   Neurosurg Clin N Am. 1991 Oct;2(4):791-806.
   
   
3. *Ala-Kokko L.
   Genetic risk factors for lumbar disc disease.
   Ann Med. 2002;34(1):42-7.
   
   
4. *Andersson GB.
   Epidemiological features of chronic low-back pain.
   Lancet. 1999 Aug 14;354(9178):581-5.
   
   
5. *Freemont AJ, Watkins A, Le Maitre C, Jeziorska M, Hoyland JA.
   Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy.
   J Pathol. 2002 Apr;196(4):374-9.
   
   
6. *Urban JP, Roberts S.
   Degeneration of the intervertebral disc.
   Arthritis Res Ther. 2003;5(3):120-30.
   
   
7. Jarvik JG, Deyo RA.
   Imaging of lumbar intervertebral disk degeneration and aging, excluding disk herniations.
   Radiol Clin North Am. 2000 Nov;38(6):1255-66.
   
   
8. Modic MT.
   Degenerative disc disease and back pain.
   Magn Reson Imaging Clin N Am. 1999 Aug;7(3):481-91.
   
   
9. *Sobajima S, Kim JS, Gilbertson LG, Kang JD.
   Innovative Treatments for Disc Degeneration Gene therapy for degenerative disc disease.
   Gene Ther. 2004 Feb;11(4):390-401.
   
   
10. *McAfee, Paul C.; Fedder, Ira L.; Saiedy, Samer; Shucosky, Erin M.; Cunningham, Bryan W. SB
    Charite Disc Replacement: Report of 60 Prospective Randomized Cases in a U.S. Center.
    Spine. 28:324-330, Journal of Spinal Disorders & Techniques: Special Online-Only Supplement to Spine, August 2003
    
    
11. *Shim, Chan Shik; Lee, Sang Ho; Park, Cheul Woong; Choi, Won Chul; Choi, Gun; Choi, Won Gyu; Lim, Sang Rak *; Lee, Ho Yeon
    Partial Disc Replacement with the PDN Prosthetic Disc Nucleus Device: Early Clinical Results.
    Spine. 28:424-433, Journal of Spinal Disorders & Techniques: Special Online-Only Supplement to Spine, August 2003
    
    
12. *Delamarter, Rick B. MD; Fribourg, David M. MD; A. Kanim, Linda E. MA; Bae, Hyun MD
    ProDisc Artificial Total Lumbar Disc Replacement: Introduction and Early Results From the United States Clinical Trial.
    Spine. 28:S167-S175, October 15, 2003.
    
    
13. *Phillips, Frank M. MD; An, Howard MD; Kang, James D. MD; Boden, Scott D. MD; Weinstein, James MD
    Biologic Treatment for Intervertebral Disc Degeneration: Summary Statement. Spine. 28:S99, August 1, 2003.

Links to PDF's

1. Regeneration and Replacement of the Intervertebral Disc
   
   
2. Pathophysiology of disk-related sciatica. I.—Evidence supporting a chemical component
   
   
3. Chapter 62: Tissue Engineering For Regeneration And Replacement Of The Intervertebral Disc
   Figure legends (PDF 3MB)
   
   
4. Chapter 62: Tissue Engineering For Regeneration And Replacement Of The Intervertebral Disc
   (PDF 383KB)
   
   
5. Epidemiological features of chronic low-back pain
   (PDF 90KB)
   
   
6. Biologic Treatment for Intervertebral Disc Degeneration
   (PDF 60KB)
   
   
7. Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy
   (PDF 140KB)
   
   
8. Functional Assessment of Engineered Tissues and Elements of Tissue Design( PDF 92KB)
   
   
9. Functional Tissue Engineering: The Role of Biomechanics
   (PDF 84KB)
   
   
10. Gene therapy for degenerative disc disease (PDF 350KB)
    
    
11. Designing materials for biology and medicine (PDF 266KB)
    
    
12. Degeneration of the intervertebral disc (PDF 425KB)
    
    
13. SB Charité Disc Replacement: Report of 60 Prospective Randomized Cases in a U.S. Center (1.19MB)
    
    
14. Partial Disc Replacement with the PDN Prosthetic Disc Nucleus Device - Early Clinical Results (PDF 500KB)
    
    
15. ProDisc Artificial Total Lumbar Disc Replacement: Introduction and Early Results From the United States - Clinical Trial (2.03MB)
    
    
16. Tissue Engineering and Reparative Medicine (PDF 174KB)
    
    

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