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  • Senior Scientist, Division of Brain Imaging & Behaviour systems – Neuroscience
    Toronto Western Research Institute
    RR Tasker Chair in Functional Neurosurgery, UHN
    Canada Research Chair in Neuroscience (Tier 1)
    Dan Family Chair in Neurosurgery
    University of Toronto

    Lecture Title: "Adjusting the Activity in Human Brain Circuits"

    READING LIST:

    1. Laxton AW, Tang-Wai DF, McAndrews MP, Zumsteg D, Wennberg R, Keren R, Wherrett J, Naglie G, Hamani C, Smith GS, Lozano AM. A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease. Annals of Neurology. 2010 Oct;68(4):521-34.
    2. Lozano AM. Harnessing plasticity to reset dysfunctional neurons. New England Journal of Medicine. 2011 Apr 7;364(14):1367-8.
    3. Lozano AM, Lipsman N. Probing and regulating dysfunctional circuits using deep brain stimulation. Neuron. 2013 Feb 6;77(3):406-24. Review.
    4. Lipsman N, Woodside DB, Giacobbe P, Hamani C, Carter JC, Norwood SJ, Sutandar K, Staab R, Elias G, Lyman CH, Smith GS, Lozano AM. Subcallosal cingulate deep brain stimulation for treatment-refractory anorexia nervosa: a phase 1 pilot trial. Lancet. 2013 Apr 20;381(9875):1361-70.
    5. Lipsman N, Schwartz ML, Huang Y, Lee L, Sankar T, Chapman M, Hynynen K, Lozano AM. MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study. Lancet Neurol. 2013 May;12(5):462-8.
    6. Elias WJ, Lipsman N, Ondo WG, Ghanouni P, Kim YG, Lee W, Schwartz M, Hynynen K, Lozano AM, Shah BB, Huss D, Dallapiazza RF, Gwinn R, Witt J, Ro S, Eisenberg HM, Fishman PS, Gandhi D, Halpern CH, Chuang R, Butts Pauly K, Tierney TS, Hayes MT, Cosgrove GR, Yamaguchi T, Abe K, Taira T, Chang JW. A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor. N Engl J Med. 2016 Aug 25;375(8):730-739.
    7. Lozano AM, Lipsman N. Probing and regulating dysfunctional circuits using deep brain stimulation. Neuron. 2013 Feb 6;77(3):406-24. Review.
    8. Holtzheimer P, Husain MM, Lisanby SH, Taylor SF, Whitworth LA, McClintock S, Slavin KV, Berman J, McKhann GM, Patil PG, Rittberg BR, Abosch A, Pandurangi AK, Holloway KL, Lam RW, Honey CR, Neimat JS, Henderson JM, DeBattista C, Rothschild AJ, Pilitsis JG, Espinoza RT, Petrides G, Mogilner AY, Matthews K,; Peichel D, Gross R, Hamani C, Lozano AM, Mayberg HS. Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomized, sham-controlled trial. Lancet Psychiatry. 2017 Nov;4(11):839-849.
    9. Lozano AM, Lipsman N, Bergman H, Brown P, Chabardes S, Chang JW, Matthews K, McIntyre C, Schlaepfer T, Schulder M, Temel Y, Volkmann J and Krauss J. Deep Brain Stimulation: Current Challenges and Future Directions. Nat Rev Neurol. 2019 Mar;15(3):148-160.
    10. Deeb W, Lozano AM, Okun M for the Advance study group. Region Deep Brain Stimulation Induced Memory Flashbacks in Alzheimer’s Disease. N Engl J Med. 2019 Aug 22;381(8):783-785.