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  • RS McLaughlin Professor and Chair
    Department of Surgery, University of Toronto

    "Glioblastoma Multiforme: Advances Beyond the Leading Edge"


    1. Diaz RJ, McVeigh PZ, O'Reilly MA, Burrell K, Bebenek M, Smith C, Etame AB, Zadeh G, Hynynen K, Wilson BC, Rutka JT.   Focused ultrasound delivery of Raman nanoparticles across the blood-brain barrier: Potential for targeting experimental brain tumors.  Nanomedicine 2014. 10: 1075-1087. 

    2. Alli S, Figueiredo CA, Golbourn B, Rutka JT.   Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery.  J Controlled Release 2018. 281: pp 29-41

    3. Coluccia D, Figueiredo CA, YiJun M, Rutka JT.   Enhancing glioblastoma treatment using cisplatin-gold-nanoparticle conjugates and targeted delivery with magnetic resonance-guided focused ultrasound.  Nanomedicine 2018. 14: pp1137-1148

    4. Bertrand KC, Faria CC, Skowron P, Rutka JT.   A functional genomics approach to identify pathways of drug resistance in medulloblastoma.   Acta Neuropathol Commun. 2018. 6: pp 146

    5. Woolman M, Kuzan-Fisher CM, Ferry I, Rutka JT, Zarrine-Afsar A. Picosecond infrared laser desorption mass spectrometry identifies medulloblastoma subgroups on intrasurgical timescales.  Cancer Res 2019. 79: pp 2426-2434

    6. Diaz RJ, Luck A, Bondoc A, Rutka JT.   Characterization of clival chordoma xenograft model reveals tumor genomic instability.  Am J Pathol 2018. 188: pp 2902-2911

    7. Terakawa Y, Agnihotri S, Goldblourn B, Nadi M, Sabha N, Smith CA, Croul SE, Rutka JT: The role of drebin in glioma migration and invasion.  Experimental Cell Research 2012: 319: pp 517-528.  PA

    8. Weeks A, Okolowsky N, Golbourn B, Ivanchuk S, Smith C, Rutka JT,: ECT2 and RASAL2 mediate mesenchymal-amoeboid transition in human astrocytoma cells.  American Journal of Pathology 2012: 181(2): pp 662-674

    9. Etame AB, Diaz RJ, O'Reilly MA, Smith CA, Mainprize TH, Hynynen K, Rutka JT: Enhanced delivery of gold nanparticles with therapeutic potential into the brain using MRI-guided focused ultrasound.  Nanomedicine 2012: 8: 1133-2

    10. Etame AB, Diaz RJ, Smith CA, Mainprize TG, Hynynen K, Rutka JT: Focused ultrasound disruption of the blood-brain barrier: A new frontier for therapeutic delivery in molecular neuro-oncology.  Neurosurgery Focus 2012: 32(1): pp E3

    11. Nagai S, Moreno O, Smith CA, Ivanchuk S, Romagnuolo R, Golbourn B, Weeks A, Seol HJ, Rutka JT: Role of the cofilin activity cycle in astrocytoma migration and invasion.  Genes & Cancer 2011: 2(9): pp 860-870